Buy Sertraline online, Buy Zoloft online
Sertraline | Zoloft is indicated in Depressive illness, Obsessive-compulsive disorder, Post-traumatic stress disorder, Panic disorder.
Therapeutic Class
SSRIs & related anti-depressant drugs
Pharmacology
Sertraline/Zoloft has potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites.
It ultimately results in an improvement of depression. Reduction of Serotonin turnover in brain by Sertraline is also another contributing fact implicated in its action. Its prolonged elimination half-life offers a benefit of once daily administration.
Dosage & Administration
Depressive illness:
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Adult: Initially 50 mg daily, increased if necessary, by increments of 50 mg over several weeks to maximum 200 mg daily. Usual maintenance dose is 50 mg daily.
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Child and adolescent less than 18 years: Not recommended.
Obsessive-compulsive disorder:
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Adult and adolescent over 13 years: Initially 50 mg daily, increased if necessary, in steps of 50 mg over several weeks. Usual dose range is 50-200 mg daily.
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Child (6-12 years): Initially 25 mg daily, increased to 50 mg daily after 1 week, further increased if necessary, in steps of 50 mg at intervals of at least 1 week (maximum 200 mg daily).
Post-traumatic stress disorder:
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Adult: Initially 25 mg daily, increased after 1 week to 50 mg daily; if response is partial and if drug is tolerated, dose can be increased in steps of 50 mg over several weeks to maximum 200 mg daily.
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Child and adolescent less than 18 years: Not recommended.