buy tradjenta online, Buy linagliptin online, Buy Tradjenta (Linagliptin) Online. Linagliptin Tradjenta 5 mg
Linagliptin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used by people with type 2 diabetes. Linagliptin Tradjenta 5 mg
Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.
Indications
Linagliptin is indicated in the treatment of type 2 diabetes mellitus to improve glycemic control in adults.
As monotherapy: in patients inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to intolerance or contraindicated due to renal impairment.
As combination therapy: in combination with metformin when diet and exercise plus metformin alone do not provide adequate glycemic control in combination with a sulphonyl urea and metformin when diet and exercise plus dual therapy with these medicinal products do not provide adequate glycemic control. Linagliptin Tradjenta 5 mg
Pharmacology
Linagliptin is indicated to improve glycemic control in patients with type 2 diabetes mellitus. Linagliptin is an inhibitor of DPP-4 (dipeptidyl peptidase-4), an enzyme that degrades the incretin hormones GLP-1 (glucagon like peptide-1) and GIP (glucose dependent insulinotropic polypeptide).
Thus, Linagliptin increases the concentrations of active incretin hormones, stimulating the release of insulin from pancreatic beta (β) cells in a glucose-dependent manner and decreasing the secretion of glucagon from pancreatic alpha (α) cells in the circulation.
Dosage & Administration
Linagliptin 5 mg once daily. If added to metformin, the dose of metformin should be maintained and linagliptin administered concomitantly. When used in combination with a sulfonylurea, a lower dose of the sulphonyl urea may be considered to reduce the risk of hypoglycemia.
Patients with renal impairment: No dose adjustment required. Linagliptin can be taken with or without a meal at any time of the day. Linagliptin Tradjenta 5 mg